ABSTRACT
Obesity is an underestimated condition of clinical and public health importance across the world. Obesity has been associated with Left ventricular hypertrophy and insulin resistance, both of which are associated with cardiovascular morbidity and mortality. The aim of present study to determine relationship between left ventricular mass index and Insulin resistance in obese subjects. Methods: The present study is a observational study conducted in Guru Nanak Dev Hospital attached to Govt. Medical college Amritsar. Total 50 normotensive nondiabetic obese subjects of both genders were included in the study. Results: There was strong positive correlation of Left Ventricular Mass Index (LVMI) with HOMA-IR. Pearson’s correlation coefficient (r) = 0.298 and P value was < 0.05. Left ventricular hypertrophy was present in 38% and 70% of obese subjects when left ventricular mass was indexed to body surface area and height respectively. Conclusion: The present study concludes that left ventricular mass index is strongly related with insulin resistance in normotensive nondiabetic obese subjects. So their earlier detection will reduce cardiovascular morbidity and mortality.
ABSTRACT
A stroke or CVA is defined by the abrupt onset of a neurologic deficit that is attributable to a focal vascular cause. Important modifiable risk factors include diabetes, hypertension, smoking, alcohol intake, sedentary life style, dyslipidemia, heart disease and OCP intake in females and non-modifiable risk factors include old age, gender predisposition and family history. The aim of study is to determine the types of stroke and presenting clinical features and modifiable and non-modifiable risk factors associated with development of stroke. Methods: The present study is a prospective observational study conducted in Teerthanker Mahaveer Medical College over a period of one year i.e January 2017 to January 2018.Total 110 cases presenting with stroke were included in the study. Results: The study shows that ischemic stroke is commoner than hemorrhagic stroke.The risk of stroke increases with age and common in males.Diabetes mellitus was seen in 29.1% cases presenting with stroke, 39.1% cases had hypertension.43.6% and 22.7 were smokers and alcoholic respectively. Dyslipidemia was present in 37.3% cases.15.4% cases had history of heart disease.17.2% cases had previous history of stroke. Conclusion: The modifiable risk factors pose a huge burden by increasing the morbidity and mortality due to stroke. Proper control of these risk factors can reduce the burden of disease.